Rapamycin, commonly known as Sirolimus, is a popular cancer drug, as well as organ transplant rejection prevention drug. The drug is also used in the treatment of a rare lung disease and in coating coronary stents. The drug was first extracted from bacterium from Easter Island, Sirolimus. Initially, the drug was used as an anti-fungal but was later found to have immunosuppressive and antiproliferative properties, leading to its abandonment as an anti-fungal agent. Mikhail Blagosklonny has done significantresearch on cancer and its treatments. He works at New York’s Rosewell Park Cancer Institute as a professor of Oncology. Besides, he is the editor-in-chief at Oncotarget where he has published various papers on aging. Over the years, he has campaigned for the use of Rapamycin in increasing the lifespan. Rapamycin is believed to be one of the best medicines because of various factors.
- Immunosuppressant Properties
The drug has immunosuppressant properties. During organ transplant, anti-rejection drugs are used to address the body’s rejection of the new organ. Most of these drugs have negative effects on the kidney. However,Rapamycin does not have such adverse effects; hence, it is preferred over other immunosuppressive drugs.Rapamycin is also used in treating tuberous sclerosis complex (TSC). Most TSC patients also suffer from facial angiofibromas and Rapamycin is used in the treatment of this condition.
- Useful in Hemolytic-Uremic Syndrome Treatment
Rapamycin is preferred in the treatment of people suffering from hemolytic-uremic syndrome. The condition is caused by a combination of conditions such as anemia, kidney failure, and lack of enough platelets prompting renal failure. Kidney transplantation is the only permanent treatment, and it requires the use of Rapamycin.
- Useful in the Treatment of Lymphangioleiomyomatosis
Rapamycin is also used in treating the unusual lung disease called lymphangioleiomyomatosis (LAM). Besides, the drug is used in coating the coronary stents. In addition, it is used in cancer treatment as it boosts the body’s response towards tumors. Mikhail Blagosklonny has carried out research on the effect of this drug on lifespan. Since the drug has a positive impact on mice, Dr. Blagosklonny believes it can enhance the lifespan of a person. More studies are still being done on the effectiveness of this drug in the treatment of muscular dystrophy and systemic lupus erythematosus (SLE).
Mikhail Blagosklonny’s Role and Contribution in Oncology
Dr. Blagosklonnyis a renowned researcher and professor determined to make treatment available to everyone irrespective of their economic status.Blagosklonny has specialized his studies on cancer and aging. Currently, he is working hard to establish the link between aging and cancer. He has been a major inspiration to not only his peers but also students wishing to advance his research in the future. Blagosklonny’s work has attracted the attention of major players in the medical field such as the impactjournals.com. His approach in the treatment of cancer is different as he is interested in reducing cost and increasing the effectiveness. In his studies, he is determined to eliminate cancerous cells without affecting the normal cells thereby reducing the recovery time.
Blagosklonny believes and hopes that his achievements in this field will inspire more people to continue with such studies in the future. He is strongly determined to change the current status quo where cancer treatment is only reserved for the rich and make accessible and affordable to all.